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Journal Articles

Organ dose reconstruction applicable for a Japanese nuclear worker cohort; J-EPISODE

Furuta, Hiroshige*; Sato, Kaoru; Nishide, Akemi*; Kudo, Shinichi*; Saigusa, Shin*

Health Physics, 121(5), p.471 - 483, 2021/11

https://doi.org/10.1097/HP.0000000000001454

Times Cited Count：1 Percentile：15.7(Environmental Sciences)

Low dose radiation induced "health effects" containing cancer risk for a Japanese radiation worker cohort is epidemiologically evaluated using the personal dose equivalent (Hp(10)). On the other hand, Hp(10) is not recommended for epidemiological evaluation of cancer risks, since the Hp(10) is widely used for radiological protection purposes. In addition, the cancer risk depends on organ doses rather than Hp(10). Thus, we developed a new method for estimating organ doses from Hp(10) of radiation workers. The developed method enables epidemiological analysis against Japanese radiation workers by considering the response characteristics of personal dosimeters, exposure geometry and energy, and body size of radiation workers in Japan. In the future, we will reconstruct organ dose conversion factor and will evaluate the risk of cancer mortality and morbidity using the organ dose in Japan.

Journal Articles

Organ absorbed dose estimation reflecting specific organ masses with simple scaling of reference doses using the organ masses

Manabe, Kentaro; Koyama, Shuji*

Radiation Protection Dosimetry, 189(4), p.489 - 496, 2020/05

AA2019-0343.pdf:0.67MB

https://doi.org/10.1093/rpd/ncaa058

Times Cited Count：1 Percentile：11.8(Environmental Sciences)

It is important for radiation protection in diagnostic nuclear medicine to estimate organ absorbed doses in consideration of person-specific parameters. This study proposes a straightforward method for estimating organ doses which reflect an individual organ masses by scaling the reference doses based on the reference human models using the inverse ratio of the individual masses to the reference organ masses. The method was tested for the administration cases of $^{rm 99m}$ Tc-labelled colloids and $^{123}$ I-labelled sodium iodine to confirm the effectiveness of the method. The discrepancies of the doses estimated by the method were sufficiently small in terms of solid organs.

Journal Articles

Construction of adult Japanese voxel phantoms with various body sizes and their applications to evaluation of organ doses due to external photon irradiation

Sato, Kaoru; Takahashi, Fumiaki

Hoken Butsuri, 52(4), p.247 - 258, 2017/12

https://doi.org/10.5453/jhps.52.247

Organ doses for dose assessment in radiation protection are derived from ICRP reference phantoms (Male:RCP-AM, Female:RCP-AF) with standard Caucasian physiques. In adult, Japanese are smaller than Caucasian. To study impact of differences in physiques between Caucasian and Japanese on organ doses, we previously constructed Japanese phantoms (Male:JM-103, Female:JF-103) with average adult Japanese physiques. In addition, adult Japanese physiques have also wide distribution. Thus, we newly modeled DJM (Male) and DJF (Female) with 8 physiques by changing the perimeters of JM-103 and JF-103. Organ doses due to external photon irradiation of DJM and DJF were calculated, and were compared with those of RCP-AM and RCP-AF. In ISO geometry at 0.3 MeV, it was found that doses of breast, colon, lung, stomach, gonad, urinary bladder, esophagus, liver and thyroid in DJM and DJF with physiques, which are applicable to most adult Japanese, agreed with those of RCP-AM and RCP-AF within 10%.

JAEA Reports

Assessment of specific absorbed fractions for photons and electrons using average adult Japanese female phantom

Manabe, Kentaro; Sato, Kaoru; Takahashi, Fumiaki

JAEA-Data/Code 2016-013, 48 Pages, 2016/12

JAEA-Data-Code-2016-013.pdf:1.3MB
JAEA-Data-Code-2016-013-appendix(CD-ROM).zip:0.47MB

In the 2007 Recommendations of the International Commission on Radiological Protection (ICRP), an effective dose is defined as a sum of equivalent doses which are calculated by using male and female reference phantoms based on Caucasian physiological data and averaged over the sexes by tissue weighting factors. Specific absorbed fractions (SAFs), which are essential for internal dosimetry, depend on the body weight and organ masses of phantoms. Then, the dose coefficients, which are committed effective doses per unit intake of radionuclides, developed by ICRP on the basis of the 2007 Recommendations reflect the physical characteristics of Caucasians and are averaged over the sexes. Meanwhile, the physiques of adult Japanese are generally smaller than those of adult Caucasians, and organ masses are also different from each other. Knowledge of the influence of race differences on dose coefficients is important to apply the sex averaged dose coefficients of ICRP to the Japanese system of radiation protection. In this study, SAFs for 25 kinds of mono-energetic electrons and photons ranging from 10 keV to 10 MeV were calculated about the combinations of 67 source regions and 42 target organs using the average adult Japanese female phantom, JF-103, incorporated with a general purpose radiation transport code, MCNPX 2.6.0. The data of this report and the previously published data of JM-103 are applicable to evaluate sex-specific and sex-averaged dose coefficients reflecting the physical characteristics of the average adult Japanese for intakes of all radionuclides not to emit other than photons and electrons.

Journal Articles

Numerical analysis of organ doses delivered during computed tomography examinations using Japanese adult phantoms with the WAZA-ARI dosimetry system

Takahashi, Fumiaki; Sato, Kaoru; Endo, Akira; Ono, Koji*; Ban, Nobuhiko*; Hasegawa, Takayuki*; Katsunuma, Yasushi*; Yoshitake, Takayasu*; Kai, Michiaki*

Health Physics, 109(2), p.104 - 112, 2015/08

https://doi.org/10.1097/HP.0000000000000299

Times Cited Count：8 Percentile：55.87(Environmental Sciences)

A dosimetry system, named WAZA-ARI, is developed to assess accurately radiation doses to persons from Computed Tomography (CT) examination patients in Japan. Organ doses were prepared to application to dose calculations in WAZA-ARI by numerical analyses using average adult Japanese human models with the Particle and Heavy Ion Transport code System (PHITS). Experimental studies clarified the radiation configuration on the table for some multi-detector row CT (MDCT) devices. Then, a source model in PHITS could specifically take into account for emissions of X-ray in each MDCT device based on the experiment results. Numerical analyses with PHITS revealed a concordance of organ doses with human body size. The organ doses by the JM phantoms were compared with data obtained using previously developed systems. In addition, the dose calculation in WAZA-ARI were verified with previously reported results by realistic NUBAS phantoms and radiation dose measurement using a physical Japanese model. The results implied that analyses using the Japanese phantoms and PHITS including source models can appropriately give organ dose data with consideration of the MDCT device and physiques of typical Japanese adults.

Journal Articles

Japanese adult male voxel phantom constructed on the basis of CT images

Sato, Kaoru; Noguchi, Hiroshi; Emoto, Yutaka*; Koga, Sukehiko*; Saito, Kimiaki

Radiation Protection Dosimetry, 123(3), p.337 - 344, 2007/02

https://doi.org/10.1093/rpd/ncl101

Times Cited Count：39 Percentile：91.36(Environmental Sciences)

A Japanese adult male voxel (volume pixel) phantom (hereinafter referred to as the JM phantom) was constructed on the basis of CT images of a healthy Japanese adult male volunteer. Body characteristics of the JM phantom were compared with those of a voxelized MIRD5 type phantom and a Japanese adult male voxel phantom which was previously developed. The voxel size of the JM phantom is 0.980.981 mm $^{3}$ . The shapes of organs of the JM phantom, even for small or complicated organs, such as thyroid and stomach, are more realistically reproduced as compared with the previous Japanese voxel phantom (voxel size: 0.980.9810 mm $^{3}$ ). Photon self-absorbed fractions for brain, kidneys, spleen, pancreas, thyroid and urinary bladder wall of JM were evaluated and were compared with those of the other phantoms. In consequence, it was suggested that the mass, shape and thickness of organs are important factors for the determination of self-absorbed fractions.

Journal Articles

Conversion from tooth enamel dose to organ doses for ESR dosimetry

Takahashi, Fumiaki; Yamaguchi, Yasuhiro

Radiation Risk Assessment Workshop Proceedings, p.71 - 78, 2003/00

Conversion from tooth enamel dose to organ doses against external photon exposure were studied in order to develop a method that can retrospectively estimate organ doses by the Electron Spin Resonance (ESR) dosimetry using tooth samples. Monte Carlo calculations using EGS4 code were performed to obtain dose to tooth enamel and organ doses by using a modified MIRD-type phantom. The Electron Spin Resonance (ESR) dosimetry using tooth samples and dose measurements using thermo-luminescence dosimeters (TLDs) were also carried out to examine dose to teeth region with a realistic physical phantom. A Voxel-type phantom was constructed from CT images of the physical phantom. Monte Carlo calculations with the Voxel-type phantom were performed to verify the results of the experiments and enamel doses calculated by use of the modified MIRD-type phantom. The obtained data are to be useful for the retrospective assessment of individual dose in past exposure events by the ESR dosimetry with tooth enamel.

Journal Articles

Conversion from tooth enamel dose to organ doses for the electron spin resonance dosimetry

Takahashi, Fumiaki; Yamaguchi, Yasuhiro; Iwasaki, Midori*; Miyazawa, Chuzo*; Hamada, Tatsuji*; Saito, Kimiaki

Journal of Nuclear Science and Technology, 39(9), p.964 - 971, 2002/09

https://doi.org/10.3327/jnst.39.964

Times Cited Count：6 Percentile：39.48(Nuclear Science & Technology)

Conversion from tooth enamel dose to organ doses was analyzed to establish a method of retrospective individual dose assessment against external photon exposure by the Electron Spin Resonance (ESR) dosimetry. Dose to tooth enamel was obtained by Monte Carlo calculations using a modified MIRD-type phantom. The calculated tooth enamel doses were verified by measurements with thermo-luminescence dosimeters inserted in a physical head phantom. Energy and angular dependences of tooth enamel dose were compared with those of other organ doses. Additional Monte Carlo calculations were performed to study the effects of human model on the tooth enamel dose with a voxel-type phantom, which was based on CT images of the physical phantom. The data derived with the modified MIRD-type phantom were applied to convert from tooth enamel dose to organ doses against external photon exposure in a hypothesized field, where scattered radiations were taken into account. The results indicated that energy distribution of photons incident to a human body should be required to evaluate precisely individual dose by the ESR dosimetry using teeth.

Journal Articles

Relations between tooth enamel dose and organ doses for the Electron Spin Resonance dosimetry against external photon exposure

Takahashi, Fumiaki; Yamaguchi, Yasuhiro; Iwasaki, Midori*; Miyazawa, Chuzo*; Hamada, Tatsuji*

Radiation Protection Dosimetry, 95(2), p.101 - 108, 2001/09

https://doi.org/10.1093/oxfordjournals.rpd.a006529

Times Cited Count：27 Percentile：85.67(Environmental Sciences)

An analysis of doses to tooth enamel and to organs was carried out to develop a method that can predict the organ doses and the effective dose by the Electron Spin Resonance (ESR) dosimetry using tooth samples for external photon exposure. Absorbed dose to tooth enamel and organ doses were obtained by Monte Carlo calculations using EGS4 code in combination with a mathematical human model with a newly defined teeth-part. The calculations gave quantitative relations between tooth enamel dose and organ doses for some cases of external photon exposure. It was also found that tooth enamel dose depends more significantly on energy of incident photons than the other organ dose or the effective dose. The obtained data are to be useful for the assessment of individual dose in past exposure events by the ESR dosimetry with tooth enamel.

Journal Articles